I don't think Cube has a specific design space unique to it. These designs are already covered by powerful cards (Standard/Modern/Eternal), Singleton (commander), Draft (Conspiracy).
There are specific cards that most cubes need (e.g. that black 5 drop) but this can be printed in any set.
There are specific cards that most cubes need (e.g. that black 5 drop) but this can be printed in any set.